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Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

Runx1 controls hematopoietic stem cell emergence and hair follicle stem cell (HFSC) activation and proliferation in adult skin. Here we use lineage tracing and mouse genetic manipulation to address the role of Runx1 in the embryonic development of HFSCs. We find Runx1 is expressed in distinct classe...

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Bibliografiske detaljer
Main Authors: Osorio, Karen M., Lilja, Karin C., Tumbar, Tudorita
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082184/
https://ncbi.nlm.nih.gov/pubmed/21464233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006068
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