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Methylphosphonate mapping of phosphate contacts critical for RNA recognition by the human immunodeficiency virus tat and rev proteins.

The HIV-1 regulatory proteins tat and rev are both RNA binding proteins which recognize sequences in duplex RNA which are close to structural distortions. Here we identify phosphate contacts which are critical for each binding reaction by use of a new method. Model RNA binding sites are constructed...

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Detalhes bibliográficos
Main Authors: Pritchard, C E, Grasby, J A, Hamy, F, Zacharek, A M, Singh, M, Karn, J, Gait, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC308214/
https://ncbi.nlm.nih.gov/pubmed/8041622
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