Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker

The past year has seen considerable developments in the use of the DNA double-strand breaks (DSBs) to evaluate genome alterations in cells undergoing a variety of genotoxic stresses in vitro and in vivo. When the γ -H2AX foci which mark the DSBs are stained, individual breaks are detectible, making...

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Main Authors: Redon, Christophe E., Nakamura, Asako J., Martin, Olga A., Parekh, Palak R., Weyemi, Urbain S., Bonner, William M.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2011
Teme:
Research Perspective
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082012/
https://ncbi.nlm.nih.gov/pubmed/21325706
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