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Acylidene oxoindoles: A new class of reversible inhibitors of human transglutaminase 2
Inhibitors of human transglutaminase 2 (TG2) are anticipated to be useful in the therapy of a variety of diseases including celiac sprue as well as certain CNS disorders and cancers. A class of 3-acylidene-2-oxoindoles was identified as potent reversible inhibitors of human TG2. Structure-activity r...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081996/ https://ncbi.nlm.nih.gov/pubmed/21215619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.12.037 |
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