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A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia
BACKGROUND: RhoGTPases have been implicated in the regulation of cancer metastasis. Invasive carcinoma cells form invadopodia, F-actin-rich matrix degrading protrusions that are thought to be important for tumor cell invasion and intravasation. Regulation of actin dynamics at invadopodial protrusion...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081966/ https://ncbi.nlm.nih.gov/pubmed/21474314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.03.039 |
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