Synthesis of “clickable” acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activation

Alkynyl- and azido-tagged 3-oxo-C(12)-acylhomoserine lactone probes have been synthesized to examine their potential utility as probes for discovering the mammalian protein target of the Pseudomonas aeruginosa autoinducer, 3-oxo-C(12)-acylhomoserine lactone. Although such substitutions are commonly...

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Detaylı Bibliyografya
Asıl Yazarlar: Garner, Amanda L., Yu, Jing, Struss, Anjali Kumari, Lowery, Colin A., Zhu, Jie, Kim, Sook Kyung, Park, Junguk, Mayorov, Alexander V., Kaufmann, Gunnar F., Kravchenko, Vladimir V., Janda, Kim D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081916/
https://ncbi.nlm.nih.gov/pubmed/21190852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.11.122
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