Φορτώνει......
Binding of gamma crystallin substrate prevents the binding of copper and zinc ions to the molecular chaperone alpha crystallin
α-crystallin is a small heat shock protein and molecular chaperone. Binding of Cu(2+) and Zn(2+) ions to α-crystallin leads to enhanced chaperone function. Sequestration of Cu(2+) by α-crystallin prevents metal-ion mediated oxidation. Here we show that binding of human γD-crystallin (HGD, a natural...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081693/ https://ncbi.nlm.nih.gov/pubmed/21417258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200091q |
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