LPS-INDUCED CCL2 EXPRESSION AND MACROPHAGE INFLUX INTO THE MURINE CENTRAL NERVOUS SYSTEM IS POLYAMINE-DEPENDENT

Increased polyamine production is observed in a variety of chronic neuroinflammatory disorders, but in vitro and in vivo studies yield conflicting data on the immunomodulatory consequences of their production. Ornithine decarboxylase (ODC) is the rate-limiting enzyme in endogenous polyamine producti...

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Detalhes bibliográficos
Main Authors: Puntambekar, Shweta S., Davis, Deirdre S., Hawel, Leo, Crane, Janelle, Byus, Craig V., Carson, Monica J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081407/
https://ncbi.nlm.nih.gov/pubmed/21237263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2010.12.016
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