Autophagy is Essential to Suppress Cell Stress and to Allow BCR-Abl-Mediated Leukemogenesis

Hematopoietic cells normally require cell extrinsic signals to maintain metabolism and survival. In contrast, cancer cells can express constitutively active oncogenic kinases such as BCR-Abl that promote these processes independent of extrinsic growth factors. When cells receive insufficient growth...

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Autores principales: Altman, Brian J., Jacobs, Sarah R., Mason, Emily F., Michalek, Ryan D., MacIntyre, Andrew N., Coloff, Jonathon L., Ilkayeva, Olga, Jia, Wei, He, You-Wen, Rathmell, Jeffrey C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081401/
https://ncbi.nlm.nih.gov/pubmed/21151168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.561
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