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Effect of Ras Inhibition in Hematopoiesis and BCR/ABL Leukemogenesis

Ras small GTPases are activated in many hematopoietic growth factor signaling and in hematological malignancies, but their role in hematopoiesis and leukemogenesis is not completely known. Here we examined the effect of Ras inhibition by a dominant negative mutant of Ras, N17 H-Ras, in adult hematop...

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Detalhes bibliográficos
Main Authors: Baum, Karina J, Ren, Ruibao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438443/
https://ncbi.nlm.nih.gov/pubmed/18577264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-1-5
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