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Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity

Resistance of tumor cells to platinum anticancer agents poses a major problem in cancer chemotherapy. One of the mechanisms associated with platinum-based drug resistance is the enhanced capacity of the cell to carry out nucleotide excision repair (NER) on platinum-damaged DNA. Endonucleases XPF and...

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Hlavní autoři: Graf, Nora, Ang, Wee Han, Zhu, Guangyu, Myint, MyatNoeZin, Lippard, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081389/
https://ncbi.nlm.nih.gov/pubmed/21452186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000724
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