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Mature Peripheral RPE Cells Have an Intrinsic Capacity to Proliferate; A Potential Regulatory Mechanism for Age-Related Cell Loss

BACKGROUND: Mammalian peripheral retinal pigmented epithelium (RPE) cells proliferate throughout life, while central cells are senescent. It is thought that some peripheral cells migrate centrally to correct age-related central RPE loss. METHODOLOGY/PRINCIPAL FINDINGS: We ask whether this proliferat...

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書誌詳細
主要な著者: Kokkinopoulos, Ioannis, Shahabi, Golnaz, Colman, Alan, Jeffery, Glen
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081302/
https://ncbi.nlm.nih.gov/pubmed/21526120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018921
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