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Mature Peripheral RPE Cells Have an Intrinsic Capacity to Proliferate; A Potential Regulatory Mechanism for Age-Related Cell Loss
BACKGROUND: Mammalian peripheral retinal pigmented epithelium (RPE) cells proliferate throughout life, while central cells are senescent. It is thought that some peripheral cells migrate centrally to correct age-related central RPE loss. METHODOLOGY/PRINCIPAL FINDINGS: We ask whether this proliferat...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081302/ https://ncbi.nlm.nih.gov/pubmed/21526120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018921 |
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