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Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein

The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 HCV virus (HCVcc) system are unknown. Two rabbit p...

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Detalhes bibliográficos
Main Authors: Vieyres, Gabrielle, Dubuisson, Jean, Patel, Arvind H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081231/
https://ncbi.nlm.nih.gov/pubmed/21084495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.028092-0
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