Whirlin Replacement Restores the Formation of the USH2 Protein Complex in Whirlin Knockout Photoreceptors

PURPOSE. Whirlin is the causative gene for Usher syndrome type IID (USH2D), a condition manifested as both retinitis pigmentosa and congenital deafness. Mutations in this gene cause disruption of the USH2 protein complex composed of USH2A and VLGR1 at the periciliary membrane complex (PMC) in photor...

Full description

Saved in:
Bibliographic Details
Main Authors: Zou, Junhuang, Luo, Ling, Shen, Zuolian, Chiodo, Vince A., Ambati, Balamurali K., Hauswirth, William W., Yang, Jun
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2011
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081228/
https://ncbi.nlm.nih.gov/pubmed/21212183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6141
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items