Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration

The pro-inflammatory cytokine IL-1β has been shown to promote angiogenesis. It can have a neurotoxic or neuroprotective effect. Here, we have studied the expression of IL-1β in vivo and the effect of the IL-1 receptor antagonist on choroidal neovascularization (CNV) and retinal degeneration (RD). IL...

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Bibliografiske detaljer
Main Authors: Lavalette, Sophie, Raoul, William, Houssier, Marianne, Camelo, Serge, Levy, Olivier, Calippe, Bertrand, Jonet, Laurent, Behar-Cohen, Francine, Chemtob, Sylvain, Guillonneau, Xavier, Combadière, Christophe, Sennlaub, Florian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081145/
https://ncbi.nlm.nih.gov/pubmed/21514452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.013
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