Tissue Microarray Cytometry Reveals Positive Impact of Homeodomain Interacting Protein Kinase 2 in Colon Cancer Survival Irrespective of p53 Function

The human p53 gene is a tumor suppressor mutated in half of colon cancers. Although p53 function appears important for proliferation arrest and apoptosis induced by cancer therapeutics, the prognostic significance of p53 mutations remains elusive. This suggests that p53 function is modulated at a po...

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Detalhes bibliográficos
Main Authors: Soubeyran, Isabelle, Mahouche, Isabelle, Grigoletto, Aude, Leste-Lasserre, Thierry, Drutel, Guillaume, Rey, Christophe, Pedeboscq, Stephane, Blanchard, France, Brouste, Veronique, Sabourin, Jean-Christophe, Bécouarn, Yves, Reiffers, Josy, Ichas, François, De Giorgi, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081143/
https://ncbi.nlm.nih.gov/pubmed/21514416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.021
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