Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax

The homothorax (hth) gene of Drosophila melanogaster is required for executing Hox functions, for head development, and for forming the proximodistal (PD) axis of the appendages. We show that alternative splicing of hth generates two types of protein isoforms, one that contains a DNA-binding homeodo...

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Bibliografiske detaljer
Main Authors: Noro, Barbara, Culi, Joaquim, McKay, Daniel J., Zhang, Wen, Mann, Richard S.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482483/
https://ncbi.nlm.nih.gov/pubmed/16778079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1412606
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