A fusion protein composed of receptor binding domain of vascular endothelial growth factor-A and constant region fragment of antibody: angiogenesis antagonistic activity

Vascular endothelial growth factor (VEGF) promotes the growth of solid tumor mainly via VEGF receptor-1 and receptor-2, which are expressed preferentially in proliferating endothelial cells. Therefore, a strategy for simultaneous blockage of both VEGF receptors may have a useful therapeutic effect i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tseng, Feng-Jen, Liu, Yen-Ku, Chung, Yo-Shong, Lin, Yu-Ling, Chen, Chia-Hung, Wang, Wan-Yi, Chen, Yu-Cheng, Tsai, Nu-Man, Cheng, Tian-Lu, Pan, Ru-Yu, Hu, Tsung-Ming, Lee, Ru-Ping, Liao, Kuang-Wen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Netherlands 2011
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081053/
https://ncbi.nlm.nih.gov/pubmed/21461946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-011-9340-2
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