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Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements
Transcription factor p63, a p53 family member, plays a role in epithelial cell development, cell cycle arrest, apoptosis, and tumorigenesis. Point mutations, primarily in the DNA binding domain (p63DBD), lead to malformation syndromes. To gain insight into differences between p63 and p53 and the imp...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080992/ https://ncbi.nlm.nih.gov/pubmed/21464285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013657108 |
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