Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y(2) receptor stimulation through S-nitrosylation of NF-κB

Cross-talk between G protein-coupled receptor (GPCR) signaling pathways serves to fine tune cellular responsiveness by neurohumoral factors. Accumulating evidence has implicated nitric oxide (NO)-based signaling downstream of GPCRs, but the molecular details are unknown. Here, we show that adenosine...

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Autors principals: Nishida, Motohiro, Ogushi, Mariko, Suda, Reiko, Toyotaka, Miyuki, Saiki, Shota, Kitajima, Naoyuki, Nakaya, Michio, Kim, Kyeong-Man, Ide, Tomomi, Sato, Yoji, Inoue, Kazuhide, Kurose, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080971/
https://ncbi.nlm.nih.gov/pubmed/21464294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017640108
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