Type II Secretion System of Pseudomonas aeruginosa: In Vivo Evidence of a Significant Role in Death Due to Lung Infection

Background. The role of toxins secreted by the type II secretion system (T2SS) of Pseudomonas aeruginosa during lung infection has been uncertain despite decades of research. Methods. Using a model of pneumonia in Toll-like receptor (TLR) 2,4(−/−) mice, we reexamined the role of the T2SS system. Fla...

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Detalhes bibliográficos
Main Authors: Jyot, Jeevan, Balloy, Viviane, Jouvion, Gregory, Verma, Amrisha, Touqui, Lhousseine, Huerre, Michel, Chignard, Michel, Ramphal, Reuben
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080898/
https://ncbi.nlm.nih.gov/pubmed/21502078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir045
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