Identification and Functional Validation of the Novel Antimalarial Resistance Locus PF10_0355 in Plasmodium falciparum

The Plasmodium falciparum parasite's ability to adapt to environmental pressures, such as the human immune system and antimalarial drugs, makes malaria an enduring burden to public health. Understanding the genetic basis of these adaptations is critical to intervening successfully against malar...

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Hauptverfasser: Van Tyne, Daria, Park, Daniel J., Schaffner, Stephen F., Neafsey, Daniel E., Angelino, Elaine, Cortese, Joseph F., Barnes, Kayla G., Rosen, David M., Lukens, Amanda K., Daniels, Rachel F., Milner, Danny A., Johnson, Charles A., Shlyakhter, Ilya, Grossman, Sharon R., Becker, Justin S., Yamins, Daniel, Karlsson, Elinor K., Ndiaye, Daouda, Sarr, Ousmane, Mboup, Souleymane, Happi, Christian, Furlotte, Nicholas A., Eskin, Eleazar, Kang, Hyun Min, Hartl, Daniel L., Birren, Bruce W., Wiegand, Roger C., Lander, Eric S., Wirth, Dyann F., Volkman, Sarah K., Sabeti, Pardis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080868/
https://ncbi.nlm.nih.gov/pubmed/21533027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001383
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