Enhanced Statistical Tests for GWAS in Admixed Populations: Assessment using African Americans from CARe and a Breast Cancer Consortium

While genome-wide association studies (GWAS) have primarily examined populations of European ancestry, more recent studies often involve additional populations, including admixed populations such as African Americans and Latinos. In admixed populations, linkage disequilibrium (LD) exists both at a f...

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Main Authors: Pasaniuc, Bogdan, Zaitlen, Noah, Lettre, Guillaume, Chen, Gary K., Tandon, Arti, Kao, W. H. Linda, Ruczinski, Ingo, Fornage, Myriam, Siscovick, David S., Zhu, Xiaofeng, Larkin, Emma, Lange, Leslie A., Cupples, L. Adrienne, Yang, Qiong, Akylbekova, Ermeg L., Musani, Solomon K., Divers, Jasmin, Mychaleckyj, Joe, Li, Mingyao, Papanicolaou, George J., Millikan, Robert C., Ambrosone, Christine B., John, Esther M., Bernstein, Leslie, Zheng, Wei, Hu, Jennifer J., Ziegler, Regina G., Nyante, Sarah J., Bandera, Elisa V., Ingles, Sue A., Press, Michael F., Chanock, Stephen J., Deming, Sandra L., Rodriguez-Gil, Jorge L., Palmer, Cameron D., Buxbaum, Sarah, Ekunwe, Lynette, Hirschhorn, Joel N., Henderson, Brian E., Myers, Simon, Haiman, Christopher A., Reich, David, Patterson, Nick, Wilson, James G., Price, Alkes L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080860/
https://ncbi.nlm.nih.gov/pubmed/21541012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001371
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