Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

While genome-wide association studies (GWAS) have primarily examined populations of European ancestry, more recent studies often involve additional populations, including admixed populations such as African Americans and Latinos. In admixed populations, linkage disequilibrium (LD) exists both at a f...

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Detalhes bibliográficos
Main Authors: Bogdan Pasaniuc, Noah Zaitlen, Guillaume Lettre, Gary K Chen, Arti Tandon, W H Linda Kao, Ingo Ruczinski, Myriam Fornage, David S Siscovick, Xiaofeng Zhu, Emma Larkin, Leslie A Lange, L Adrienne Cupples, Qiong Yang, Ermeg L Akylbekova, Solomon K Musani, Jasmin Divers, Joe Mychaleckyj, Mingyao Li, George J Papanicolaou, Robert C Millikan, Christine B Ambrosone, Esther M John, Leslie Bernstein, Wei Zheng, Jennifer J Hu, Regina G Ziegler, Sarah J Nyante, Elisa V Bandera, Sue A Ingles, Michael F Press, Stephen J Chanock, Sandra L Deming, Jorge L Rodriguez-Gil, Cameron D Palmer, Sarah Buxbaum, Lynette Ekunwe, Joel N Hirschhorn, Brian E Henderson, Simon Myers, Christopher A Haiman, David Reich, Nick Patterson, James G Wilson, Alkes L Price
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-04-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC3080860?pdf=render
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