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Accessing a Hidden Conformation of the Maltose Binding Protein Using Accelerated Molecular Dynamics
Periplasmic binding proteins (PBPs) are a large family of molecular transporters that play a key role in nutrient uptake and chemotaxis in Gram-negative bacteria. All PBPs have characteristic two-domain architecture with a central interdomain ligand-binding cleft. Upon binding to their respective li...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080849/ https://ncbi.nlm.nih.gov/pubmed/21533070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002034 |
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