Engineered Resistance to Plasmodium falciparum Development in Transgenic Anopheles stephensi

Transposon-mediated transformation was used to produce Anopheles stephensi that express single-chain antibodies (scFvs) designed to target the human malaria parasite, Plasmodium falciparum. The scFvs, m1C3, m4B7, and m2A10, are derived from mouse monoclonal antibodies that inhibit either ookinete in...

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Hlavní autoři: Isaacs, Alison T., Li, Fengwu, Jasinskiene, Nijole, Chen, Xiaoguang, Nirmala, Xavier, Marinotti, Osvaldo, Vinetz, Joseph M., James, Anthony A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080844/
https://ncbi.nlm.nih.gov/pubmed/21533066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002017
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