Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo

CONTEXT: Mitochondrial ATP production is important in the regulation of glucose-stimulated insulin secretion. Genetic factors may modulate the capacity of the β-cells to secrete insulin and thereby contribute to the risk of type 2 diabetes. OBJECTIVE: The aim of this study was to identify genetic lo...

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Detalhes bibliográficos
Main Authors: Olsson, Anders H, Rönn, Tina, Ladenvall, Claes, Parikh, Hemang, Isomaa, Bo, Groop, Leif, Ling, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: BioScientifica 2011
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080761/
https://ncbi.nlm.nih.gov/pubmed/21325017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-10-0995
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