Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Smoking is a risk factor for most of the diseases leading in mortality1. We conducted genome-wide association (GWA) meta-analyses of smoking data within the ENGAGE consortium to search for common alleles associating with the number of cigarettes smoked per day (CPD) in smokers (N=31,266) and smoking...

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Autores principales: Thorgeirsson, Thorgeir E., Gudbjartsson, Daniel F., Surakka, Ida, Vink, Jacqueline M., Amin, Najaf, Geller, Frank, Sulem, Patrick, Rafnar, Thorunn, Esko, Tõnu, Walter, Stefan, Gieger, Christian, Rawal, Rajesh, Mangino, Massimo, Prokopenko, Inga, Mägi, Reedik, Keskitalo, Kaisu, Gudjonsdottir, Iris H., Gretarsdottir, Solveig, Stefansson, Hreinn, Thompson, John R., Aulchenko, Yurii S., Nelis, Mari, Aben, Katja K., den Heijer, Martin, Dirksen, Asger, Ashraf, Haseem, Soranzo, Nicole, Valdes, Ana M, Steves, Claire, Uitterlinden, André G, Hofman, Albert, Tönjes, Anke, Kovacs, Peter, Hottenga, Jouke Jan, Willemsen, Gonneke, Vogelzangs, Nicole, Döring, Angela, Dahmen, Norbert, Nitz, Barbara, Pergadia, Michele L., Saez, Berta, De Diego, Veronica, Lezcano, Victoria, Garcia-Prats, Maria D., Ripatti, Samuli, Perola, Markus, Kettunen, Johannes, Hartikainen, Anna-Liisa, Pouta, Anneli, Laitinen, Jaana, Isohanni, Matti, Huei-Yi, Shen, Allen, Maxine, Krestyaninova, Maria, Hall, Alistair S, Jones, Gregory T., van Rij, Andre M., Mueller, Thomas, Dieplinger, Benjamin, Haltmayer, Meinhard, Jonsson, Steinn, Matthiasson, Stefan E., Oskarsson, Hogni, Tyrfingsson, Thorarinn, Kiemeney, Lambertus A., Mayordomo, Jose I., Lindholt, Jes S, Pedersen, Jesper Holst, Franklin, Wilbur A., Wolf, Holly, Montgomery, Grant W., Heath, Andrew C., Martin, Nicholas G., Madden, Pamela A.F., Giegling, Ina, Rujescu, Dan, Järvelin, Marjo-Riitta, Salomaa, Veikko, Stumvoll, Michael, Spector, Tim D, Wichmann, H-Erich, Metspalu, Andres, Samani, Nilesh J., Penninx, Brenda W., Oostra, Ben A., Boomsma, Dorret I., Tiemeier, Henning, van Duijn, Cornelia M., Kaprio, Jaakko, Gulcher, Jeffrey R., McCarthy, Mark I., Peltonen, Leena, Thorsteinsdottir, Unnur, Stefansson, Kari
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080600/
https://ncbi.nlm.nih.gov/pubmed/20418888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.573
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