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Aryl hydrocarbon-induced interactions at multiple DNA elements of diverse sequence--a multicomponent mechanism for activation of cytochrome P4501A1 (CYP1A1) gene transcription.

In vivo footprinting experiments, augmented with gel shift and transfection analyses suggest that activation of the CYP1A1 gene by aryl hydrocarbons may be a multicomponent process. During the first 30 minutes of exposure to aryl hydrocarbon carcinogens and environmental contaminants, in vivo footpr...

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Autors principals: Robertson, R W, Zhang, L, Pasco, D S, Fagan, J B
Format: Artigo
Idioma:Inglês
Publicat: 1994
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC308058/
https://ncbi.nlm.nih.gov/pubmed/8202380
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