GATA4 Deficiency Impairs Ovarian Function in Adult Mice

Transcription factor GATA4 is expressed in granulosa cells and, to a lesser extent, in other ovarian cell types. Studies of mutant mice have shown that interactions between GATA4 and its cofactor, ZFPM2 (also termed FOG2), are required for proper development of the fetal ovary. The role of GATA4 in...

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Main Authors: Kyrönlahti, Antti, Vetter, Melanie, Euler, Rosemarie, Bielinska, Malgorzata, Jay, Patrick Y., Anttonen, Mikko, Heikinheimo, Markku, Wilson, David B.
Format: Artigo
Sprog:Inglês
Udgivet: Society for the Study of Reproduction, Inc. 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080425/
https://ncbi.nlm.nih.gov/pubmed/21248289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.110.086850
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