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Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects

Congenital diaphragmatic hernia (CDH) is an often fatal birth defect that is commonly associated with pulmonary hypoplasia and cardiac malformations. Some investigators hypothesize that this constellation of defects results from genetic or environmental triggers that disrupt mesenchymal cell functio...

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Detalhes bibliográficos
Main Authors: Jay, Patrick Y., Bielinska, Malgorzata, Erlich, Jonathan M., Mannisto, Susanna, Pu, William T., Heikinheimo, Markku, Wilson, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808541/
https://ncbi.nlm.nih.gov/pubmed/17069789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.09.050
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