Expression from the tyrosine aminotransferase promoter (nt -350 to +1) is liver-specific and dependent on the binding of both liver-enriched and ubiquitous trans-acting factors.

The rat tyrosine aminotransferase(TAT) gene promoter (nucleotides -350 to +1; TAT0.35) was able to sustain liver-specific expression both ex vivo in transient transfection (TAT-expressing H411EC3 hepatoma cells vs. TAT non-expressing CCL1.2 fibroblasts) and in in vitro transcription (rat liver vs. s...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Schweizer-Groyer, G, Groyer, A, Cadepond, F, Grange, T, Baulieu, E E, Pictet, R
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 1994
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7911235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.9.1583
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