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Expression from the tyrosine aminotransferase promoter (nt -350 to +1) is liver-specific and dependent on the binding of both liver-enriched and ubiquitous trans-acting factors.

The rat tyrosine aminotransferase(TAT) gene promoter (nucleotides -350 to +1; TAT0.35) was able to sustain liver-specific expression both ex vivo in transient transfection (TAT-expressing H411EC3 hepatoma cells vs. TAT non-expressing CCL1.2 fibroblasts) and in in vitro transcription (rat liver vs. s...

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Dettagli Bibliografici
Autori principali: Schweizer-Groyer, G, Groyer, A, Cadepond, F, Grange, T, Baulieu, E E, Pictet, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC308033/
https://ncbi.nlm.nih.gov/pubmed/7911235
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