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Manifestations and mechanisms of stem cell aging

Adult stem cells exist in most mammalian organs and tissues and are indispensable for normal tissue homeostasis and repair. In most tissues, there is an age-related decline in stem cell functionality but not a depletion of stem cells. Such functional changes reflect deleterious effects of age on the...

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Библиографические подробности
Главные авторы: Liu, Ling, Rando, Thomas A.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080271/
https://ncbi.nlm.nih.gov/pubmed/21502357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010131
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