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Stem cell ageing and non-random chromosome segregation

Adult stem cells maintain the mature tissues of metazoans. They do so by reproducing in such a way that their progeny either differentiate, and thus contribute functionally to a tissue, or remain uncommitted and replenish the stem cell pool. Because ageing manifests as a general decline in tissue fu...

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Bibliografiske detaljer
Main Authors: Charville, Gregory W., Rando, Thomas A.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001309/
https://ncbi.nlm.nih.gov/pubmed/21115534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0279
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