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Phospholipase D1, but Not D2, Regulates Protein Secretion Via Rho/ROCK in a Ras/Raf-Independent, MEK-Dependent Manner in Rat Lacrimal Gland

PURPOSE. A prior study showed that cholinergic agonists activate phospholipase D (PLD). The purpose of this study was to determine whether cholinergic agonists use the PLD pathway to alter protein secretion and to identify the molecular signaling components of this pathway in rat lacrimal gland acin...

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Autores principales: Hodges, Robin R., Guilbert, Erin, Shatos, Marie A., Natarajan, Viswanathan, Dartt, Darlene A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Association for Research in Vision and Ophthalmology, Inc. 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080178/
https://ncbi.nlm.nih.gov/pubmed/21212180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6209
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