Phospholipase D1, but Not D2, Regulates Protein Secretion Via Rho/ROCK in a Ras/Raf-Independent, MEK-Dependent Manner in Rat Lacrimal Gland

PURPOSE. A prior study showed that cholinergic agonists activate phospholipase D (PLD). The purpose of this study was to determine whether cholinergic agonists use the PLD pathway to alter protein secretion and to identify the molecular signaling components of this pathway in rat lacrimal gland acin...

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Main Authors: Hodges, Robin R., Guilbert, Erin, Shatos, Marie A., Natarajan, Viswanathan, Dartt, Darlene A.
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080178/
https://ncbi.nlm.nih.gov/pubmed/21212180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6209
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