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The role of Co(2+) in the crystallization of human SENP1 and comments on the limitations of automated refinement protocols

Metal ions often stabilize intermolecular contacts between macromolecules, thereby promoting crystallization. When interpreting a medium-resolution electron-density map of the catalytic domain of human sentrin-specific protease 1 (SENP1), a strong feature indicative of an ordered divalent cation was...

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Bibliografiske detaljer
Main Authors: Rimsa, Vadim, Eadsforth, Thomas, Hunter, William N.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080145/
https://ncbi.nlm.nih.gov/pubmed/21505236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111005835
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