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Two high-resolution structures of the human E3 ubiquitin ligase Siah1
Siah1 is an E3 ubiquitin ligase that contributes to proteasome-mediated degradation of multiple targets in key cellular processes and which shows promise as a therapeutic target in oncology. Structures of a truncated Siah1 bound to peptide-based inhibitors have been reported. Here, new crystallizati...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
International Union of Crystallography
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855715/ https://ncbi.nlm.nih.gov/pubmed/24316825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113031448 |
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