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Cocrystallization studies of full-length recombinant butyrylcholinesterase (BChE) with cocaine

Human butyrylcholinesterase (BChE; EC 3.1.1.8) is a 340 kDa tetrameric glycoprotein that is present in human serum at about 5 mg l(−1) and has well documented therapeutic effects on cocaine toxicity. BChE holds promise as a therapeutic that reduces and finally eliminates the rewarding effects of coc...

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מידע ביבליוגרפי
Main Authors: Asojo, Oluwatoyin Ajibola, Asojo, Oluyomi Adebola, Ngamelue, Michelle N., Homma, Kohei, Lockridge, Oksana
פורמט: Artigo
שפה:Inglês
יצא לאור: International Union of Crystallography 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080143/
https://ncbi.nlm.nih.gov/pubmed/21505234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111004805
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