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5-HT(1B) autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior

BACKGROUND: 5-HT(1B) autoreceptors regulate release of serotonin from terminals of dorsal raphe nucleus (DRN) projections. 5-HT(1B) expression in the DRN correlates with behavioral measures of emotion, and viral-mediated overexpression of 5-HT(1B) receptors in the middle DRN reduces measures of fear...

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Autores principales: McDevitt, Ross A, Hiroi, Ryoko, Mackenzie, Scott M, Robin, Nicholas C, Cohn, Aaron, Kim, Jeansok J, Neumaier, John F
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080128/
https://ncbi.nlm.nih.gov/pubmed/21353664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.12.029
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