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Complement Protein C1q-Mediated Neuroprotection Is Correlated with Regulation of Neuronal Gene and MicroRNA Expression

Activation of the complement cascade, a powerful effector mechanism of the innate immune system, is associated with neuroinflammation but also with elimination of inappropriate synapses during development. Synthesis of C1q, a recognition component of the complement system, occurs in brain during isc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Benoit, Marie E., Tenner, Andrea J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080046/
https://ncbi.nlm.nih.gov/pubmed/21368058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3932-10.2011
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