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Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin
The serine protease thrombin plays a major role in thrombosis and haemostasis. This has driven interest in thrombin inhibitors as potential antithrombotic drugs. Here, the crystallization and preliminary crystallographic analysis of human α-thrombin in complex with three noncovalent peptide inhibit...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
International Union of Crystallography
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079972/ https://ncbi.nlm.nih.gov/pubmed/21206024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110043472 |
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