Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin

The serine protease thrombin plays a major role in thrombosis and haemostasis. This has driven interest in thrombin inhibitors as potential antithrombotic drugs. Here, the crystallization and preliminary crystallographic analysis of human α-­thrombin in complex with three noncovalent peptide inhibit...

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Hauptverfasser: Carvalho Figueiredo, Ana, Clement, Cristina C., Philipp, Manfred, Barbosa Pereira, Pedro José
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2010
Schlagworte:
Crystallization Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079972/
https://ncbi.nlm.nih.gov/pubmed/21206024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110043472
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