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Modeling HBx induced hepatocellular carcinoma in mice using the Sleeping Beauty transposon system

The mechanisms associated with hepatitis B viral (HBV) induced hepatocellular carcinoma (HCC) remain elusive and currently, there are no well-established animal models to study this disease. Using the Sleeping Beauty transposon as a delivery system, we introduced an oncogenic component of HBV, namel...

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Hlavní autoři: Keng, Vincent W., Tschida, Barbara R., Bell, Jason B., Largaespada, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079950/
https://ncbi.nlm.nih.gov/pubmed/21374658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24091
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