Impaired odontogenic differentiation of senescent dental mesenchymal stem cells is associated with loss of Bmi-1 expression

INTRODUCTION: Dental mesenchymal stem cells (dMSCs) may differentiate into odontoblast-like cells and form mineralized nodules. In the current study, we investigated the effects of senescence on odontogenic differentiation of dMSCs. METHODS: dMSCs were serially subcultured until senescence. Telomere...

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Main Authors: Mehrazarin, Shebli, Oh, Ju Eun, Chung, Christine L., Chen, Wei, Kim, Reuben H., Shi, Songtao, Park, No-Hee, Kang, Mo K.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079884/
https://ncbi.nlm.nih.gov/pubmed/21496667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joen.2011.02.009
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