Pharmacological Blockade of 5-HT(7) Receptors as a Putative Fast Acting Antidepressant Strategy

Current antidepressants still display unsatisfactory efficacy and a delayed onset of therapeutic action. Here we show that the pharmacological blockade of serotonin 7 (5-HT(7)) receptors produced a faster antidepressant-like response than the commonly prescribed antidepressant fluoxetine. In the rat...

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Bibliographic Details
Main Authors: Mnie-Filali, Ouissame, Faure, Céline, Lambás-Señas, Laura, Mansari, Mostafa El, Belblidia, Hassina, Gondard, Elise, Etiévant, Adeline, Scarna, Hélène, Didier, Anne, Berod, Anne, Blier, Pierre, Haddjeri, Nasser
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079839/
https://ncbi.nlm.nih.gov/pubmed/21326194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.13
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