Protein Kinase C Inhibition Rescues Manic-Like Behaviors and Hippocampal Cell Proliferation Deficits in the Sleep Deprivation Model of Mania

BACKGROUND: Recent studies revealed that bipolar disorder may be associated with deficits of neuroplasticity. Additionally, accumulating evidence has implicated alterations of the intracellular signaling molecule protein kinase C (PKC) in mania. METHODS: Using sleep deprivation (SD) as an animal mod...

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Dettagli Bibliografici
Pubblicato in:Int J Neuropsychopharmacol
Autori principali: Abrial, Erika, Bétourné, Alexandre, Etiévant, Adeline, Lucas, Guillaume, Scarna, Hélène, Lambás-Señas, Laura, Haddjeri, Nasser
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368890/
https://ncbi.nlm.nih.gov/pubmed/25577667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu031
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