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Use of Instrumental Variable in Prescription Drug Research with Observational Data: A Systematic Review

OBJECTIVE: Instrumental variable (IV) analysis may offer a useful approach to the problem of unmeasured confounding in prescription drug research if the IV is: 1) strongly and unbiasedly associated to treatment assignment; and 2) uncorrelated with factors predicting the outcome (key assumptions). ST...

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Detalles Bibliográficos
Main Authors: Chen, Yong, Briesacher, Becky A.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079803/
https://ncbi.nlm.nih.gov/pubmed/21163621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2010.09.006
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